Emerging Homochiral Porous Materials for Enantiomer Separation

Efficient resolution of racemates chiral molecules is great significance in the pharmaceutical, agrochemical, fragrances, and food additives industries. Emerging homochiral porous materials such as metal–organic frameworks, covalent-organic porous-organic cages, metal-organic cages with ultrahigh surface area, controllable pore chemistry ample recognition sites are promising for efficient resolution, which display excellent properties separation applications. This review summarizes design synthesis strategies construction materials, including direct synthesis, post-synthesis, induction synthesis. Following this, applications emerging enantioselective adsorption, chromatography, membrane-based highlighted. Finally, challenges this area discussed, future perspectives provided.